The Bicolor Blenny needs a tank of at least 30 gallons with plenty of sandy subsrtate and scattered rocks for hiding. The Bicolor Blenny is usually a peaceful tank member, as long as they are in a tank with plenty of space. In smaller encloshers, they tend to pick on other blennies, gobies, and even dartfishes. They are also considered not reef safe for they will eat fleshy corals. They should be fed frozen or live brine shrimp and other frozen foods.